Diffuse Large B-Cell Lymphoma of the Caecum in A Non-HIV Patient - A Rare Occurrence: Case Report

Primary gastrointestinal (GI) lymphomas constitute less than 8 % per cent of total gut neoplasms. Most of them are Non-Hodgkin’s type of Lymphomas. Among the Extra-nodal tissues Gastro-intestinal tract is the most common site followed by Head and Neck region, Central nervous system, Thorax, Spleen, Adrenal glands, Uro-genital tract, skin and Bone. The stomach is the most common location of GI lymphomas; followed by the small intestine and large intestine. Although gastrointestinal tract is the most common extra-nodal site yet caecum involvement is rarest. It has low incidence but favorable outcome. Histologically, B-cell lymphomas are by far the most frequent type found in this location, gastrointestinal lymphomas are a diverse group of neoplasms, many of which are characterized by distinctive clinicopathological settings. Diffuse large B-cell lymphoma and marginal-zone lymphoma of mucosa-associated lymphoid tissue are commonly encountered, but other less common entities can pose diagnostic challenges, mimicking reactive, benign and malignant conditions. Ultrasound (US) is often the first imaging modality used in patients with vague abdominal symptoms and can detect several patterns of involvement in cases of lymphoma. Computerized tomography (CT) is valuable for the staging of the disease. We report a rare case of a 35 year old gentleman who presented with colicky abdominal pain, vomiting, intussusception and bleeding per rectum was diagnosed as a case of caecal lymphoma on histopathology.